Moles, warts, skin tags, and other "lumps and bumps" can be removed with radiosurgery. Skin tags are harmless growths that protrude from the skin and are typically small, flesh-coloured, and soft. This method eliminates skin tags and other lumps rapidly with minimal scarring. The area around the wire electrode is the only cut area, while radio waves are used rather than a scalpel. This means that mole and tag removal, as well as seborrheic keratosis, veins on the face and capillary removal, and cherry angioma removal, can be performed without the need for sutures or scarring.

This procedure uses a tissue as a barrier against low-temperature, high-frequency radio waves. Tissue generates heat through resistance to the passage of high-frequency waves. Because the intracellular water is heated to temperatures well above its boiling point, the internal pressure of the tissue mass is increased. As the pressure inside the cell increases, the cell membranes rupture, resulting in a cutting action.

Without having to burn the tissue, as is typically necessary during such surgery, the heat generated by the evaporation of water in the subcellular tissue spreads, coagulating cellular proteins and resulting in haemostasis or the cessation of blood flow. Electrodes as varied as fine needles, wire loops, and scalpel blades are used to create a wide range of lesions. The site of the procedure is numbed with a local anaesthetic. The extent of scarring after skin tag removal is proportional to the size of the tag. Upon completion of the healing process, the final look will be identical to the surrounding skin.